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Advise sufferers that: Tramadol Hydrochloride Extended-Release is for oral use only and may be swallowed entire. The capsule should not be chewed, dissolved, crushed or break up. Tramadol Hydrochloride Extended-Launch may well result in seizures and/or serotonin syndrome with concomitant utilization of serotonergic brokers (which includes SRIs, NRI